All anabolic steroids suppress natural testosterone production. However, the rate of suppression often varies greatly from one steroid to the next. Although it does suppress natural testosterone production, Primobolan’s rate of suppression is much less dramatic than many anabolic steroids. In a therapeutic plan, it is actually possible to keep the total rate of suppression below 50%. This could be low enough to keep some from falling into a low level condition despite the reduction. However, performance level doses will be another story. Dramatic suppression is all but assured with such doses making the inclusion of exogenous testosterone extremely important. Men who do not include exogenous testosterone will more than likely fall into a low testosterone condition. Not only does this carry numerous possible bothersome symptoms, it is extremely unhealthy. Women, despite needing testosterone will not have a need for exogenous therapy when using Primobolan.
Once the use of Primo and all anabolic steroids has come to an end, natural testosterone production will begin again. You will find this is one of the easiest steroids to recover from when it comes to testosterone production. Most men are encouraged to implement a Post Cycle Therapy (PCT) plan once use is discontinued. This will speed the recovery process up. It will, however, not return you to normal on its own. This will still take time. However, a PCT plan will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. Those who do not implement a PCT plan, while they may recover it will take far longer. There’s really no reason to forgo the PCT process if you’re going to be off cycle for any decent length of time.
An important note on natural testosterone recovery. Natural recovery assumes no prior low testosterone condition existed. It also assumes severe damage was not done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) through improper steroidal supplementation practices.
On 24 February 2006 episode of SmackDown! , Guerrero attacked Randy Orton when Orton began to insult Eddie and the heritage of the Guerreros. Guerrero was soon dragged out by security.  On 27 February episode of Raw , Guerrero faced off against Shelton Benjamin in a qualifying match for the Money in the Bank ladder match at WrestleMania 22 . During the match, Orton interfered and hit Guerrero with the RKO , allowing Benjamin to get the pinfall victory.  He proceeded to unsuccessfully challenge Benjamin for the WWE Intercontinental Championship . In a segment that aired on WWE Unlimited , an emotional Guerrero decided to quit WWE, in storyline , after believing he had let his family, Eddie, and the fans down and expressed his doubts about being a wrestler. 
Mysterio made his WWE debut on the July 25, 2002, episode of SmackDown! as a fan favorite in a match against Chavo Guerrero, which Mysterio won.  He eventually began a feud with Kurt Angle , which culminated in a match at SummerSlam that Angle won after forcing Mysterio to submit to the ankle lock .  He later formed a tag team with Edge ; the two participated in a tournament for the newly created and SmackDown!-exclusive WWE Tag Team Championship . They lost to Kurt Angle and Chris Benoit in the finals of the tournament at No Mercy ;  the match was voted match of the year by the Wrestling Observer Newsletter . After they failed to win the title, Mysterio and Edge defeated Los Guerreros in a number one contender's match on the October 24 episode of SmackDown! to earn a title shot.  Two weeks later on November 7, they defeated Angle and Benoit in a two out of three falls match to win their first Tag Team Championship.  They soon lost the tag titles to Los Guerreros in a Triple Threat Elimination match that also involved former champions Angle and Benoit at Survivor Series .  Shortly after the loss, Mysterio and Edge disbanded as a tag team.