Athletes abuse amphetamines because they experience a decreased sense of fatigue. However, athletes do sustain increases in blood pressure, increases in heart rate, redistribution of blood flow to skeletal muscles, and mobilization of energy substrates. One of the uses of amphetamines is to promote weight loss. This can be dangerous because it can cause body fat percent to drop to dangerous levels in some athletes. Amphetamines suppress hunger and can increase the risk of athletes reducing glycogen This may reduce the performance capabilities of athletes. Amphetamine abuse by athletes is not recommended and any athlete using these drugs should be counseled.
Anticoagulants: Patients on anticoagulants such as warfarin should be carefully monitored during anabolic steroid therapy as anabolic steroids may increase sensitivity to oral anticoagulants which may require a concomitant reduction in anticoagulant dosage to achieve a desirable prothrombin time (PT). Anticoagulant patients should be monitored regularly during anabolic steroid therapy, particularly during initiation and termination of therapy. Warfarin patients should have INR and PT monitored throughout androgen therapy and warfarin dosages titrated to achieve the desired INR and PT. Such patients should be monitored for occult bleeding.