In one small scale clinical trial of depressed patients, an improvement of symptoms which included anxiety, lack of drive and desire was observed.  In patients with dysthymia , unipolar , and bipolar depression significant improvement was observed.  In this series of studies, mesterolone lead to a significant decrease in luteinizing hormone and testosterone levels.  In another study, 100 mg mesterolone cipionate was administered twice monthly.  With regards to plasma testosterone levels, there was no difference between the treated versus untreated group, and baseline luteinizing hormone levels were minimally affected. 
ketoconazole (nizoral) shampoo on my face and shoulders to treat AAS induced acne with fantastic success.
I'm only taking TRT (250mg/week) but it's enough to give me acne that I otherwise would not have. I'm fairly sure it would work on acne induced by higher doses as well.
The only downside is a bit of soreness and dryness, mostly on my nose and cheekbones. I've been using it twice per day, and it may be possible to prevent the acne with less frequent usage while avoiding this minor discomfort.
To recap everything mentioned here in this article, remember the following:
1) HPTA suppression is virtually inevitable. Even a single 100mg injection of nandrolone will cause full suppression for almost a week and you won’t return to a normal HPTA for at least two weeks. Plan your cycle accordingly and overshoot your goals knowing you’ll lose something.
2) Injection volume and concentration are important. When available, opt for the highest concentration on a mg/ml basis.
3) Injection site is important. The best place for maximal plasma levels seems to be the glutes.
4) Side chain ester length is probably the single most important factor in influencing plasma levels. The shorter the ester (and the half life) the better. You may have to inject more often, but in the long run it’ll be worth it.